John D Bartlett Selected Research

Amelogenesis Imperfecta

10/2019	ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development.
1/2019	Mutations in RELT cause autosomal recessive amelogenesis imperfecta.
9/2014	Shear bond strength of dentin and deproteinized enamel of amelogenesis imperfecta mouse incisors.
9/2013	Dental enamel development: proteinases and their enamel matrix substrates.
1/2012	Transcription factor FoxO1 is essential for enamel biomineralization.
12/2011	Matrix metalloproteinase 20 promotes a smooth enamel surface, a strong dentino-enamel junction, and a decussating enamel rod pattern.
8/2008	Mutational spectrum of FAM83H: the C-terminal portion is required for tooth enamel calcification.
6/2008	Functions of KLK4 and MMP-20 in dental enamel formation.
5/2006	A developmental comparison of matrix metalloproteinase-20 and amelogenin null mouse enamel.
12/2002	Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.

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John D Bartlett Research Topics

Disease

10	Amelogenesis Imperfecta 10/2019 - 12/2002
9	Dental Fluorosis 01/2021 - 06/2005
3	Dental Caries (Decay, Dental) 01/2021 - 09/2012
2	Dental Enamel Hypoplasia 01/2019 - 12/2002
2	Neoplasms (Cancer) 12/2016 - 06/2004
1	Miosis 11/2021
1	Infections 01/2019
1	Uveal melanoma 12/2016
1	Cataract (Cataracts) 01/2016
1	Tooth Diseases 01/2012
1	Odontogenic Tumors (Dental Tissue Neoplasm) 06/2004
1	Dwarfism 01/2003
1	Metabolic Bone Diseases (Osteopenia) 01/2003
1	Craniofacial Abnormalities 01/2003
1	Fibrosarcoma 03/2002
1	Melanoma (Melanoma, Malignant) 03/2002
1	Neoplasm Metastasis (Metastasis) 03/2002

Drug/Important Bio-Agent (IBA)

7	FluoridesIBA 01/2021 - 09/2008
3	AmelogeninIBA 09/2014 - 12/2002
3	Proteins (Proteins, Gene)FDA Link 09/2013 - 06/2008
3	Matrix Metalloproteinase 20IBA 12/2011 - 12/2002
2	RELTIBA 10/2019 - 01/2019
2	Sirtuin 1IBA 12/2015 - 02/2014
1	Brimonidine Tartrate (Alphagan)FDA LinkGeneric 11/2021
1	Trace Elements (Biometals)IBA 01/2021
1	hydroxide ionIBA 03/2020
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2019
1	Iodine-125IBA 12/2016
1	Silicone OilsIBA 12/2016
1	Sodium Hypochlorite (Clorox)IBA 09/2014
1	Composite ResinsIBA 09/2014
1	AntioxidantsIBA 08/2014
1	enamel matrix proteinsIBA 08/2014
1	Vitamin E FDA LinkGeneric 08/2014
1	Transcription Factors (Transcription Factor)IBA 01/2012
1	Collagen Type XVIII (Type XVIII Collagen)IBA 06/2004
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 01/2003
1	Diphosphonates (Bisphosphonates)IBA 03/2002
1	Alendronate (Alendronate Sodium)FDA LinkGeneric 03/2002
1	Matrix Metalloproteinases (MMPs)IBA 03/2002
1	Fibronectins (Fibronectin)IBA 03/2002
1	CTTHWGFTLC peptideIBA 03/2002
1	matrigelIBA 03/2002

Therapy/Procedure

1	Brachytherapy 12/2016
1	Vitrectomy 12/2016
1	Lasers (Laser) 01/2016
1	Fluoride Treatment 06/2005